Neurobiology of Nondeclarative Memory: A Selected Review on Motor There is extensive evidence and it is widely recognized that motor skill learning is spared in patients with dense amnesia. However, the neural substrates of motor skill learning are a continuing topic of research and a current matter of debate. This review focuses on the differential contribution of the striatum ... Article
Article  |   April 01, 2014
Neurobiology of Nondeclarative Memory: A Selected Review on Motor
Author Affiliations & Notes
  • Sara Cavaco
    Servico de Neurologia, Centro Hospitalar do Porto/ICBAS/UMIB, Portugal
    Division of Behavioral Neurology and Cognitive Neuroscience, University of Iowa, Iowa City, IA
  • Financial Disclosure: Sara Cavaco is a Neuropsychologist at Centro Hospitalar do Porto/ICBAS/UMIB and a Postdoctoral Research Scholar at the University of Iowa.
    Financial Disclosure: Sara Cavaco is a Neuropsychologist at Centro Hospitalar do Porto/ICBAS/UMIB and a Postdoctoral Research Scholar at the University of Iowa.×
  • Nonfinancial Disclosure: Sara Cavaco has no nonfinancial interests related to the content of this article.
    Nonfinancial Disclosure: Sara Cavaco has no nonfinancial interests related to the content of this article.×
Article Information
Attention, Memory & Executive Functions / Articles
Article   |   April 01, 2014
Neurobiology of Nondeclarative Memory: A Selected Review on Motor
SIG 2 Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders, April 2014, Vol. 24, 43-49. doi:10.1044/nnsld24.2.43
SIG 2 Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders, April 2014, Vol. 24, 43-49. doi:10.1044/nnsld24.2.43

There is extensive evidence and it is widely recognized that motor skill learning is spared in patients with dense amnesia. However, the neural substrates of motor skill learning are a continuing topic of research and a current matter of debate. This review focuses on the differential contribution of the striatum and the cerebellum to learning skills that require either motor sequence or motor adaptation. A brief overview of the current knowledge helps understand why certain patient populations, such as patients with Parkinson's disease and patients with cerebellar ataxia, experience difficulty with motor skill acquisition.

Acknowledgements
The author received financial support from Bial Foundation (grants 03/02 and 201/08) to study the neural structures involved in motor skill learning.
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