Motor Speech Function in Young Males With Fragile X Syndrome Fragile X syndrome (FXS) is the most common genetic cause of mental retardation, affecting approximately 1 in 1,200 males and 1 in 2,500 females (Abbeduto & Hagerman, 1997). Some of the common characteristics that appear in individuals with fragile X syndrome include mental retardation (with an incidence of approximately ... Article
Article  |   June 01, 2006
Motor Speech Function in Young Males With Fragile X Syndrome
Author Affiliations & Notes
  • Elizabeth F. Barnes
    University of North Carolina at Chapel Hill, Chapel Hill, NC
Article Information
Speech, Voice & Prosodic Disorders / Special Populations / Genetic & Congenital Disorders / Articles
Article   |   June 01, 2006
Motor Speech Function in Young Males With Fragile X Syndrome
SIG 2 Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders, June 2006, Vol. 16, 3-7. doi:10.1044/nnsld16.2.3
SIG 2 Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders, June 2006, Vol. 16, 3-7. doi:10.1044/nnsld16.2.3
Fragile X syndrome (FXS) is the most common genetic cause of mental retardation, affecting approximately 1 in 1,200 males and 1 in 2,500 females (Abbeduto & Hagerman, 1997). Some of the common characteristics that appear in individuals with fragile X syndrome include mental retardation (with an incidence of approximately 85%), attention deficits, hyperactivity, sensory and tactile defensiveness, gross and fine motor impairments, and speech and language deficits (Abbeduto & Hagerman; Hagerman, 2002; Kau, Meyer, & Kaufman, 2002). In addition to these mental and physical characteristics, children with fragile X syndrome may also exhibit social avoidance and other pragmatic deficits. In fact, it is estimated that as many as 15–25% of all males with fragile X syndrome also have a diagnosis of autism (Bailey, Hatton, & Skinner, 1998; Dykens & Volkmar, 1997; Hagerman, 2002).
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